What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found naturally in every cell of the body, and it plays an essential role in energy metabolism. NAD+ is necessary for the functioning of NAD-dependent enzymes, which are involved in many biochemical processes, including:

• oxidative phosphorylation

• DNA repair

• gene expression.

NAD+ levels tend to decline with age, which has been linked to several aging-related diseases.

“Restoration of NAD+ levels in old or diseased animals can promote health and extend lifespan” -Cell Metab. 2018 Mar 6;27(3):529-547.

NAD+ & Your Health

Increasing NAD+ levels through the supplementation of NAD+ precursors, such as nicotinamide mononucleotide (NMN), has been shown to have several potential health benefits.

Supplementation may help improve cognitive functioning, increase longevity, and even help protect against certain chronic diseases. So, if you're looking for a way to turn back the hands of time, NAD+ supplementation might just be the answer!

NAD+ Treatments

Many NAD+ boosting supplements on the market have been developed to restore NAD+ levels and promote longevity. The most popular NAD+ supplement is Nicotinamide Mononucleotide (NMN), a precursor of NAD+. NMN supplementation has been shown to restore NAD+ levels in animal models, but its long term benefits for humans remain unclear.

The NAD+ biosynthesis pathway is complex, involving several enzymes and metabolic intermediates. NAD+ itself can be recycled through NAD+ salvage pathways, but NAD+ levels decline with age due to decreased NAD+ recycling, as well as increased NAD+ degradation by PARP1. Thus, NAD+ supplementation may provide an effective way to increase NAD+ levels in the body and promote longevity.

Overall, NAD+ is an important coenzyme that plays a crucial role in energy metabolism and cell function.

Remember, NAD+ may not be a fountain of youth, but it's definitely a powerful tool to help keep you feeling young and energized for years to come. So why not give NAD+ supplementation a try today?